S-Adenosyl Methionine Prevents Endothelial Dysfunction by Inducing Heme Oxygenase-1 in Vascular Endothelial Cells | September 2013

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NCBI>Molecules and Cells

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887983/

Exhaustive Exercise and Post-Exercise Protein Plus Carbohydrate Supplementation Affect Plasma and Urine Concentrations of Sulfur Amino Acids, the Ratio of Methionine to Homocysteine and Glutathione in Elite Male Cyclists | December 2020

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Frontiers in Physiology

https://www.frontiersin.org/articles/10.3389/fphys.2020.609335/full

Associations Between Intake of Folate, Methionine, and Vitamins B-12, B-6 and Prostate Cancer Risk in American Veterans | June 2012

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Journal of Cancer Epidemiology

https://www.hindawi.com/journals/jce/2012/957467/

S-Adenosyl Methionine (SAMe) versus Celecoxib for the Treatment of Osteoarthritis Symptoms: A Double-Blind Cross-Over Trial | February 2004

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BMC Musculoskeletal Disorders

http://bmcmusculoskeletdisord.biomedcentral.com/articles/10.1186/1471-2474-5-6

Dietary B Vitamin and Methionine Intakes and Lung Cancer Risk among Female Never Smokers in China | October 2012

Articles (Manuscripts-Versions)

PubMed Central>Cancer Causes and Control

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518409/

Effect of Protein and Methionine Intakes on Plasma Homocysteine Concentrations: A 6-Mo Randomized Controlled Trial in Overweight Subjects | December 2002

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American Journal of Clinical Nutrition

https://doi.org/10.1093/ajcn/76.6.1202

Visualizing Central Effects of S-Adenosyl-L-Methionine (SAMe), a Natural Molecule with Antidepressant Properties, by Pharmaco-EEG Mapping | September 2002

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International Journal of Neuropsychopharmacology

https://doi.org/10.1017/S1461145702002924

Dietary Intake of B Vitamins and Methionine and Prostate Cancer Incidence and Mortality | April 2012

Abstracts

Cancer Causes and Control

https://link.springer.com/article/10.1007/s10552-012-9954-5

Folates and S-Adenosylmethionine for Major Depressive Disorder | July 2012

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Canadian Journal of Psychiatry

https://journals.sagepub.com/doi/abs/10.1177/070674371205700703

Folate, Vitamin B6, Vitamin B12 and Methionine Intakes and Risk for Nasopharyngeal Carcinoma in Chinese Adults: A Matched Case-Control Study | October 2015

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British Journal of Nutrition

http://dx.doi.org/10.1017/S0007114515004146

S-Adenosyl Methionine (SAMe) for Depression in Adults | October 2016

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Cochrane Database of Systematic Reviews

https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD011286.pub2/abstract

Associations of Dietary Folate, Vitamins B6 and B12 and Methionine Intake with Risk of Breast Cancer among African American and European American Women | August 2013

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International Journal of Cancer

https://onlinelibrary.wiley.com/doi/abs/10.1002/ijc.28466

Maternal Betaine Status, But Not that of Choline or Methionine, Is Inversely Associated with Infant Birth Weight | May 2019

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British Journal of Nutrition

https://doi.org/10.1017/S0007114519000497

The Origins, Evolution, and Future of Dietary Methionine Restriction | May 2022

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Annual Review of Nutrition

https://www.annualreviews.org/doi/abs/10.1146/annurev-nutr-062320-111849

Dietary and Supplementary Betaine: Acute Effects on Plasma Betaine and Homocysteine Concentrations Under Standard and Postmethionine Load Conditions in Healthy Male Subjects | March 2008

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American Journal of Clinical Nutrition

https://doi.org/10.1093/ajcn/87.3.577

Intake of Folate, Vitamins B6, B12 and Methionine and Risk of Pancreatic Cancer in a Large Population-Based Case-Control Study | May 2009

Articles (Manuscripts-Versions)

PubMed Central>Cancer Causes and Control

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306816/

Association of Vitamin B6, Vitamin B12 and Methionine with Risk of Breast Cancer: A Dose-Response Meta-Analysis | October 2013

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British Journal of Cancer

https://www.nature.com/articles/bjc2013438

Folate, Vitamin B6, Vitamin B12, and Methionine Intakes and Risk of Stroke Subtypes in Male Smokers | February 2008

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American Journal of Epidemiology

https://doi.org/10.1093/aje/kwm395

Effects of Randomized Supplementation of Methionine or Alanine on Cysteine and Glutathione Production During the Early Phase of Treatment of Children with Edematous Malnutrition | March 2014

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American Journal of Clinical Nutrition

https://doi.org/10.3945/ajcn.113.062729

Implication of the Folate-Methionine Metabolism Pathways in Susceptibility to Follicular Lymphomas | June 2006

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Blood-American Society of Hematology

http://www.bloodjournal.org/content/108/1/278.full

Serum Choline, Methionine, Betaine, Dimethylglycine, and Trimethylamine-N-Oxide in Relation to Pancreatic Cancer Risk in Two Nested Case-Control Studies in Asian Populations (Meetings-Events) | July 2017

Abstracts

Cancer Research

https://doi.org/10.1158/1538-7445.AM2017-2273

Association of One-Carbon Metabolism-Related Vitamins (Folate, B6, B12), Homocysteine and Methionine with the Risk of Lung Cancer: Systematic Review and Meta-Analysis | October 2018

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Frontiers in Oncology

https://www.frontiersin.org/articles/10.3389/fonc.2018.00493/full

The Plasma S-Adenosylmethionine Level Is Associated with the Severity of Hepatitis B-Related Liver Disease | January 2015

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Medicine

https://journals.lww.com/md-journal/Fulltext/2015/01040/The_Plasma_S_adenosylmethionine_Level_is.38.aspx

S-Adenosylmethionine Biosynthesis is a Targetable Metabolic Vulnerability of Cancer Stem Cells | February 2019

Articles (Manuscripts-Versions)

PubMed Central>Breast Cancer Research and Treatment

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494685/

Therapeutic Potential of the Natural Compound S-Adenosylmethionine as a Chemoprotective Synergistic Agent in Breast, and Head and Neck Cancer Treatment: Current Status of Research | November 2020

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International Journal of Molecular Sciences

https://doi.org/10.3390/ijms21228547

Dietary Intake of B Vitamins and Methionine and Risk of Lung Cancer | August 2011

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European Journal of Clinical Nutrition

https://www.nature.com/articles/ejcn2011157

Choline-Related Supplements Improve Abnormal Plasma Methionine-Homocysteine Metabolites and Glutathione Status in Children with Cystic Fibrosis | March 2007

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American Journal of Clinical Nutrition

https://doi.org/10.1093/ajcn/85.3.702

St. John’s Wort and S-Adenosyl Methionine as “Natural” Alternatives to Conventional Antidepressants in the Era of the Suicidality Boxed Warning: What Is the Evidence for Clinically Relevant Benefit? | March 2011

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NCBI>Alternative Medicine Review

https://www.ncbi.nlm.nih.gov/pubmed/21438644

Alcohol, Folate, Methionine, and Risk of Incident Breast Cancer in the American Cancer Society Cancer Prevention Study II Nutrition Cohort | February 2003

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Cancer Epidemiology, Biomarkers and Prevention

http://cebp.aacrjournals.org/content/12/2/161.full

S-Adenosyl Methionine Improves Early Viral Responses and Interferon-Stimulated Gene Induction in Hepatitis C Nonresponders (SAMe) | September 2010

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PubMed Central>Gastroenterology

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3021477/

Bioavailability of S-Adenosyl Methionine and Impact on Response in a Randomized Controlled Trial in Major Depressive Disorder | May 2012

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PubMed Central>Journal of Clinical Psychiatry

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156851/

A Double-Blind, Randomized Parallel-Group, Efficacy and Safety Study of Intramuscular S-Adenosyl-L-Methionine 1,4-Butanedisulphonate (SAMe) versus Imipramine in Patients with Major Depressive Disorder | December 2002

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International Journal of Neuropsychopharmacology

https://doi.org/10.1017/S1461145702003085

Oral Supplementation with a Nutraceutical Containing Echinacea, Methionine and Antioxidant/Immunostimulating Compounds in Patients with Cutaneous Viral Warts | June 2011

Abstracts

Giornale Italiano di Dermatologia e Venereologia

https://www.minervamedica.it/en/journals/dermatologia-venereologia/article.php?cod=R23Y2011N03A0191

S-Adenosylmethionine Inhibits Colorectal Cancer Cell Migration through Mirna-Mediated Targeting of Notch Signaling Pathway | July 2022

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International Journal of Molecular Sciences

https://www.mdpi.com/1422-0067/23/14/7673

Changes in Dietary Intake of Methionine, Folate/Folic Acid and Vitamin B12 and Survival in Postmenopausal Women with Breast Cancer: A Prospective Cohort Study | November 2022

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Nutrients

https://www.mdpi.com/2072-6643/14/22/4747

Homocysteine and Lipids: S-Adenosyl Methionine as a Key Intermediate | March 2009

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FEBS Letters

https://febs.onlinelibrary.wiley.com/doi/full/10.1016/j.febslet.2009.03.038

Deficiencies of Folate and Vitamin B(6) Exert Distinct Effects on Homocysteine, Serine, and Methionine Kinetics | December 2001

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American Journal of Physiology – Endocrinology and Metabolism

https://www.physiology.org/doi/full/10.1152/ajpendo.2001.281.6.e1182

Circulating Folate, Vitamin B6, and Methionine in Relation to Lung Cancer Risk in the Lung Cancer Cohort Consortium (LC3) | July 2017

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Journal of the National Cancer Institute

https://doi.org/10.1093/jnci/djx119

Influence of Age, Sex and Vitamin Status on Fasting and Post-Methionine Load Plasma Homocysteine Levels | September 2002

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Haematologica

http://www.haematologica.org/content/87/9/957.full

Cobalamin Deficiency with and without Neurologic Abnormalities: Differences in Homocysteine and Methionine Metabolism | April 2003

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Blood-American Society of Hematology

http://bloodjournal.hematologylibrary.org/content/101/8/3302.full

Interactive Effects of Methionine and Lead Intake on Cognitive Function among Chinese Adults | October 2022

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Nutrients

https://www.mdpi.com/2072-6643/14/21/4561

Betaine as a Determinant of Postmethionine Load Total Plasma Homocysteine Before and After B-Vitamin Supplementation | December 2003

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Arteriosclerosis, Thrombosis, and Vascular Biology

https://www.ahajournals.org/doi/full/10.1161/01.atv.0000114569.54976.31

S-Adenosylmethionine (SAMe) for Neuropsychiatric Disorders: A Clinician-Oriented Review of Research | June 2017

Abstracts

Journal of Clinical Psychiatry

https://doi.org/10.4088/JCP.16r11113

S-Adenosyl-L-Methionine Augmentation in Patients with Stage II Treatment-Resistant Major Depressive Disorder: An Open Label, Fixed Dose, Single-Blind Study | April 2013

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Scientific World Journal

https://www.hindawi.com/journals/tswj/2013/204649/

Methionine and Vitamin B-Complex Ameliorate Antitubercular Drugs-Induced Toxicity in Exposed Patients | September 2017

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Pharmacology Research and Perspectives

http://onlinelibrary.wiley.com/doi/10.1002/prp2.360/full

S-Adenosylmethionine May Mitigate Obstructive Sleep Apnea in an Adult with Down Syndrome: A Case Report | February 2022

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Nature and Science of Sleep

https://doi.org/10.2147/NSS.S350350

Dietary Folate, Methionine, Riboflavin, and Vitamin B-6 and Risk of Sporadic Colorectal Cancer | December 2008

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Journal of Nutrition

https://doi.org/10.3945/jn.108.091157

Preliminary Results of a Randomized Controlled Trial Carried Out with a Fixed Combination of S-Adenosyl-L-Methionine and Betaine versus Amitriptyline in Patients with Mild Depression | February 2015

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International Journal of General Medicine

https://doi.org/10.2147/IJGM.S79518

B Vitamins, Methionine and Alcohol Intake and Risk of Colon Cancer | June 2011

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PLOS ONE

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0021102

S-Adenosylmethionine (SAM-e) for the Treatment of Depression in People Living with HIV/AIDS | November 2004

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BMC Psychiatry

https://bmcpsychiatry.biomedcentral.com/articles/10.1186/1471-244X-4-38